Review:
Uniprot Knowledgebase (uniprotkb)
overall review score: 4.8
⭐⭐⭐⭐⭐
score is between 0 and 5
UniProt Knowledgebase (UniProtKB) is a comprehensive and freely accessible database that provides detailed information on protein sequences, annotations, functions, structures, and related biological data. It serves as a central resource for researchers in bioinformatics, molecular biology, and related fields to access curated and high-quality protein data.
Key Features
- Curated database with manually annotated protein information
- Integration of experimental data and computational analyses
- Extensive cross-references to other biological databases
- Regular updates ensuring current and accurate data
- Rich functional annotations including enzyme activities, subcellular locations, and interactions
- Accessible via a user-friendly web interface and REST API
- Supports large-scale bioinformatics research and analysis
Pros
- Highly comprehensive and reliable protein data
- Extensively curated to ensure accuracy
- User-friendly interface with multiple search options
- Enables integration with various bioinformatics tools
- Constantly maintained and updated
Cons
- Can be complex for new users to navigate without prior background
- Occasional delays in updates for very new or rare proteins
- Some annotations may be limited for lesser-studied proteins