Review:

Fret (fluorescence Resonance Energy Transfer)

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FRET (Fluorescence Resonance Energy Transfer) is a phenomenon in which energy is transferred between two fluorophores, leading to a change in the fluorescent emission of one fluorophore when another is nearby.

Key Features

  • Energy transfer between fluorophores
  • Used in molecular biology and biochemistry
  • Can measure distances at the nanoscale level

Pros

  • High sensitivity for measuring molecular interactions
  • Non-destructive technique
  • Can be used in live cell imaging

Cons

  • Requires careful optimization of experimental conditions
  • Limited to small distances for accurate measurements

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Last updated: Sun, Mar 22, 2026, 10:22:13 AM UTC